What is N-Acetylcysteine?

N-acetylcysteine (NAC) is widely used as an antidote to acetaminophen overdose (14) and its administration has been reported to be beneficial in various medical fields such as dermatology, neurology, gastroenterology, nephrology and pulmonology. Its effectiveness is largely based on the free radical scavenging property of NAC.

Supplementation with NAC significantly increases the levels of intracellular glutathione, the body’s major anti-oxidant (15)Glutathione is critically important for detoxifying an array of toxic substances and free radical–generating molecules. It thereby exerts a profound protective effect on cells. (16) 

As this powerful antioxidant is frequently depleted in patients with stress and aging, RHEODERM will replenish glutathione levels and will thus decrease oxidative stress and cellular damage.

14.Brok J, Buckley N, Gluud C. Interventions for paracetamol (acetaminophen) overdose. Cochrane Database Syst Rev. 2006;(2):CD003328.

15. Dekhuijzen PN. Antioxidant properties of N-acetylcysteine: their relevance in relation to chronic obstructive pulmonary disease. Eur Respir J. 2004;23(4):629-636.

16.Dickinson DA, Moellering DR, Iles KE, et al. Cytoprotection against oxidative stress and the regulation of glutathione synthesis. Biol Chem. 2003;384(4):527-537.